San Diego is a major city in California with an estimated population of 1,355,896 as of July 1, 2013. San Diego is the eighth-largest city in the United States and second-largest in California. San Diego is the birthplace of California and is known for its mild year-round climate, natural deep-water harbor, extensive beaches, long association with the U.S. Navy, and recent emergence as a healthcare and biotechnology development center.
